In October 1940 the unit re-equipped with Wellingtons and became a night bomber squadron moving to RAF Snaith on the 10^th  July 1941, remaining there until the 15^th October 1942 before moving to North Africa to begin operations against targets in Sicily and Italy. Later the squadron moved to the Italian mainland to continue its raids against enemy targets. The unit disbanded on 5^th October 1944, reforming again on the 1^st November at RAF Fiskerton from C flight of 550 squadron flying Lancasters. It carried out bombing operations against German targets for the rest of the war disbanding again on 7^th November 1945. It’s last incarnation came on 1^st August 1959 when it was reformed one last time as a Thor ballistic missile unit at RAF Carnaby. It disbanded for the last time on 9^th April 1963.

During its time at RAF Snaith  205 of the 150 Squadron airmen lost their lives on active duty. Their lives are remembered on the airfield itself at Pollington Airfield Memorial Garden, along with 687 from 51 Squadron. The garden is accessible 365 days a year and reunions take place biannually in May and November. It is a beautiful memorial to those who served at RAF Snaith.